![]() ![]() There are 215 drug interactions with rosuvastatin. A daily glass of grapefruit juice increases blood levels of simvastatin and lovastatin by about 260 if taken at the same time (about 90 if taken 12 hours apart), and atorvastatin by about 80 (whenever taken). Switch to professional interaction data Rosuvastatin drug interactions Do not stop using any medications without first talking to your doctor. ![]() The risk of very serious side effects is extremely low. That’s because grapefruit affects an enzyme that normally. Rhabdomyolysis can cause extreme muscle pain, liver damage, kidney failure and death. In fact, studies have shown greater reductions in cholesterol levels when taking statins and grapefruit together. Rather, grapefruit seems to boost statins’ power to act on the body, while also potentially boosting its side effects. It is important to tell your doctor about all other medications you use, including vitamins and herbs. This is not the case with grapefruit and statins. Avoid taking an antacid within 2 hours after you take ezetimibe and rosuvastatin. Talk to your doctor or pharmacist if you have any questions or concerns. Call your doctor immediately if you have fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark urine, pale stools, and/or yellowing of the skin or eyes, as these may be signs and symptoms of liver damage. You should limit the use of alcohol while being treated with these medications. Rosuvastatin may cause liver problems and using it with substantial quantities of ethanol may increase that risk. Roszet (rosuvastatin / ezetimibe) is a combination of two medications that work together to lower cholesterol levels.
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